One bold idea. That’s all it takes.  Unorthodox thinking is essential to overcoming the most persistent challenges in global health. Vaccines were first developed over 200 years ago because revolutionary thinkers took an entirely new approach to preventing disease.  Grand Challenges Explorations fosters innovation in global health research. The Bill & Melinda Gates Foundation has committed $100 million to encourage scientists worldwide to expand the pipeline of ideas to fight our greatest health challenges.  Launched in 2008, more than 800 Grand Challenge Explorations grants have been awarded to innovative, early-stage projects in more than 50 countries.

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